NIAID Asthma Studies
To better understand the problem of inner-city asthma, the National Institutes of Health sponsored the National Cooperative Inner-City Asthma Study (NCICAS). NCICAS was an eight site, seven cities project which first evaluated the risk factors for asthma severity among inner-city children and then evaluated an intervention to improve the morbidity. Childhood asthma in the inner-city was found to be a multifaceted problem in the first phase of NCICAS. As a result, a multidimensional approach was taken during the intervention phase of NCICAS. This approach proved to effectively reduce the burden of asthma in the inner-city.
The design of the National Cooperative Inner-City Asthma Study did not allow the separate components of the intervention to be evaluated as to their effectiveness or importance. The Inner-City Asthma Study (ICAS) was created to look at the importance of the various components. ICAS was sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Environmental Health Sciences (NIEHS), both of which are part of the National Institutes of Health (NIH). ICAS focused on the indoor environment, education of children and caregivers, and education of physicians. ICAS evaluated two interventions. The first was a communication/physician feedback system that provided physicians with up-to-date information on patient clinical status, medication use, and health care utilization. The second intervention included an extensive intervention in the home environments of these children, including cockroach and mold mitigation, reduction of dust mite exposure and training for avoidance of environmental triggers.The CARAT is based upon the National Cooperative Inner-City Asthma Study (NCICAS) as well as published asthma research with input from nationally renowned asthma specialists.
For further information on the two NIAID asthma studies and for general information on asthma, please go to: